Innovations in Single Cell Omics

28th and 29th of May 2026
Barcelona

The human body consists of trillions of cells, but a mutation in one of them can cause cancer.

This example demonstrates that biology is not a process driven by averages and highlights the importance of single cell-level studies. The last years have seen a rapid expansion of the field of single-cell genomics, which has enabled paradigm shifts in many fields of biological sciences, ranging from evolutionary biology over stem cell biology to cancer research. 

The ISCO conference  is co-organized by leading  centres  for  genomic and  biomedical  research in  Berlin and Barcelona and brings together  young  single cell researchers from different disciplines to  enable scientific exchange and  foster new international collaborations. Topics are innovations in single-cell and spatially-resolved technologies, new computational approaches and applications in the medical arena. This year, an additional focused session on single-cell epi-genomics will be included in the program.

ISCO puts special emphasis on providing networking opportunities for PhD students and postdocs, with a large number of talks from selected abstract, a poster session and dedicated time to facilitate exchange with colleagues and informal discussions.

The 5th edition of ISCO is back in Barcelona!

Keynote Speakers

Christoph Bock
CeMM Research Center for Molecular Medicine
Austria
Bart Deplancke
École Polytechnique Fédérale de Lausanne
Switzerland
Sabrina L. Spencer
University of Colorado Boulder
US

Invited Speakers

William Allen
Stanford University School of Medicine
US
Rebecca Berrens
University of Oxford
UK
Tim Coorens
EMBL-EBI
UK
Hsiu-Chuan Lin
Centre for Genomic Regulation
Spain
Alba Meira
Dana-Farber Cancer Institute
US
Ferran Nadeu
Hospital Clínic Barcelona
Spain
Yusuf Roohani
Arc Institute
US

Program

Day 1 - May 28 2026

08:30 - 09:30
Arrival and registration
09:30
Opening Remarks
09:35
Christoph Bock (CeMM Research Center for Molecular Medicine, Austria) Opening Keynote "Programmed Cells? Single-cell Biology and Cell Engineering for Immunity and Cancer"
Session 1: Perturbations - Chair Alejo Rodríguez-Fraticelli
10:20
Yusuf Roohani (Arc Institute, US) "Title TBC"
10:50
Selected talk from abstracts received
11:10
Coffee Break
Session 1: Perturbations (continuation) - Chair Alejo Rodríguez-Fraticelli
11:40
Hsiu-Chuan Lin (Centre for Genomic Regulation, Spain) "Single-cell screening for human cell fate engineering"
12:10
Selected talk from abstracts received
12:30
Selected talk from abstracts received
12:50
Sponsored talk
13:05
Lunch Break
Session 2: Cellular phylogenies and Lineages - Chair Leif Ludwig
14:30
Tim Coorens (EMBL-EBI, UK) "Somatic evolution and phylogenetics: Tracing development and the origins of disease"
15:00
Selected talk from abstracts received
15:20
Selected talk from abstracts received
15:40
Sponsored talk
15:55
Short Break
Session 3: Translation – Chair Ashley Sanders
16:20
Ferran Nadeu (Hospital Clínic Barcelona, Spain) "An evolutionary journey across the CLL course"
16:50
Selected talk from abstracts received
17:10
Selected talk from abstracts received
17:30
Selected talk from abstracts received
17:50
Poster Session
20:00
Dinner at Carpe Diem Restaurant

Day 2 - May 29 2026

09:30 - 10:00
Arrival and late registration
10:00
Sabrina L. Spencer (University of Colorado Boulder, US) Keynote talk "Title TBC"
Session 4: Spatial omics – Chair Lars Velten
10:45
William Allen (Stanford University School of Medicine, US) "Title TBC"
11:15
Selected talk from abstracts received
11:35
Coffee Break
Session 5 | Topic in focus session: Single-cell epigenomics – Chair Elisabetta Mereu
12:05
Rebecca Berrens (University of Oxford, UK) "Title TBC"
12:35
Selected talk from abstracts received
12:55
Selected talk from abstracts received
13:15
Sponsored talk
13:30
Lunch Break
Session 5 | Topic in focus session: Single-cell epigenomcs (Continuation) – Chair Elisabetta Mereu
14:45
Alba Meira (Dana-Farber Cancer Institute, US) "Scalable single-cell DNA methylation reveals a stepwise differentiation logic disrupted in hematopoietic clonal expansions"
15:15
Selected talk from abstracts received
15:35
Bart Deplancke (École Polytechnique Fédérale de Lausanne, Switzerland) Keynote talk "Title TBC"
16:20
Closing Remarks

Organizers

Organizers

Lars Velten
Single Cell and Synthetic Genomics of Blood Formation Group Leader
Centre for Genomic Regulation
Elisabetta Mereu
Cellular Systems Genomics Group Leader
Josep Carreras Leukaemia Research Institute
Alejo Rodríguez-Fraticelli
Quantitative Stem Cell Dynamics Group Leader
Institute for Research in Biomedicine

Co-Organizers

Stefanie Grosswendt
From Cells to Tissues Group Leader
Berlin Institute of Health
Simon Haas
Systems Hematology, Stem Cells & Precision Medicine Group Leader
Berlin Institute of Health
Leif Ludwig
Stem Cell Dynamics and Mitochondrial Genomics Group Leader
Berlin Institute of Health
Ashley Sanders
Genome instability and somatic mosaicism Group Leader
Max Delbrück Center for Molecular Medicine

Supported by

Platinum Sponsors

Bonsai Lab
Takara Bio
Mission Bio

Gold Sponsors

Parse Biosciences
Diagnóstica Longwood